SubtiBank SubtiBank
gatC
The second international online conference #Subtillery2021 will be held 14th - 18th June - save the date, for more information see the conference website!

The 21st International Conference on Bacilli has been postponed to 2022 and will take place in Prague.

gatC

production of glutamyl-tRNA(Gln)
locus
BSU_06670
pI
4.60
mw
10.72 kDa
protein length
96 aa Sequence Blast
gene length
291 bp Sequence Blast
function
translation
product
glutamyl-tRNA(Gln) amidotransferase (subunit C)
essential
yes
ec
6.3.5.7
synonyms
yerL,yedA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.10|Aminoacyl-tRNA synthetases]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]

    • Gene

    Coordinates
    728,732 729,022

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • ATP + H2O + L-glutamine + L-glutamyl-tRNAGln --> ADP + H+ + L-glutamate + L-glutaminyl-tRNAGln + phosphate (according to UniProt)
  • ATP + H2O + L-aspartyl-tRNAAsn + L-glutamine --> ADP + 2 H+ + L-asparaginyl-tRNAAsn + L-glutamate + phosphate (according to UniProt)

    • Protein family

  • gatC family (single member, according to UniProt)

    • Modification

  • phosphorylated on Arg-3 [Pubmed|22517742]

    • Structure

  • [PDB|2DF4] ([protein|FA88576A405F8C92C83BE74985039DC02E1F6C94|GatA]-[protein|F9C088D2DB3E99FDF961DE1B78A9B81279F204C9|GatB]-[protein|4A6AB40A91B4821B99E2FECD1C4E523321B8BDEA|GatC] complex from ''Staphylococcus aureus'') [Pubmed|16809541]

    • Expression and Regulation

    Operons

    genes
    [gene|4A6AB40A91B4821B99E2FECD1C4E523321B8BDEA|gatC]-[gene|FA88576A405F8C92C83BE74985039DC02E1F6C94|gatA]-[gene|F9C088D2DB3E99FDF961DE1B78A9B81279F204C9|gatB]
    description
    [pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • MGNA-A928 (yerL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/928 NBRP B. subtilis, Japan]

    • References

  • 9342321,20882017,22517742,16809541