The second international online conference
#Subtillery2021 will be held 14th - 18th June - save the date, for more information see the
conference website!
The 21st
International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
phrH
secreted regulator of the activity of phosphatase [protein|BA85E2C2E2A6B76FAFA31EBDBF466324C9B021C8|RapH]
function
control of [SW|sporulation] initiation
product
secreted regulator of the activity of phosphatase [protein|BA85E2C2E2A6B76FAFA31EBDBF466324C9B021C8|RapH]
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.3|Control of response regulators/ other][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.6|Other protein controlling the activity of the phosphorelay][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.6|Other protein controlling the activity of the phosphorelay][category|SW 6|Groups of genes] → [category|SW 6.8|Short peptides]Gene
Coordinates
752,079 752,252
The protein
Protein family
[SW|phr family] (according to UniProt)[SW|Localization]
secreted as hexapeptide TDRNTT [Pubmed|21908671], uptake by the ([protein|05752B9C4EA7ACD579D65D028B7DF1861F3840CB|OppD]-[protein|38AD697B6C9967B8BD7496E31264A21F6D0A9DEE|OppF])-([protein|B0A3C7B253FB1DA1D4BC9D1D564905ECE8A65BC1|OppB]-[protein|DDBCE73B6AF39E5D669475479186C93F287DA9FC|OppC])-[protein|302DFA46D73E18C4663468ED6033C55056744475|OppA] [SW|ABC transporter] [Pubmed|21908671]Expression and Regulation
Operons
genes
[gene|4FA7D6E6316A6FC71C10C692D125833263894020|phrH]
description
[Pubmed|21908671]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|21908671], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|RghR]: repression, [Pubmed|16553878], in [regulon|972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|RghR regulon]regulation
''[protein|search|rapH]'': repressed by [protein|search|RghR] [Pubmed|16553878]view in new tabgenes
[gene|BA85E2C2E2A6B76FAFA31EBDBF466324C9B021C8|rapH]-[gene|4FA7D6E6316A6FC71C10C692D125833263894020|phrH]
description
[Pubmed|21908671]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|21908671], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|RghR]: repression, [Pubmed|16553878], in [regulon|972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|RghR regulon][protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|ComK]: activation, [Pubmed|11948146,11918817], in [regulon|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|ComK regulon][protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]regulation
''[protein|search|rapH]'': repressed by [protein|search|RghR] [Pubmed|16553878]view in new tabBiological materials
Mutant
BKE06839 ([gene|4FA7D6E6316A6FC71C10C692D125833263894020|phrH]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE06839 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGCCAGACACATCATCACTT, downstream forward: _UP4_TAGGGCTTTTTCTTGCTTTABKK06839 ([gene|4FA7D6E6316A6FC71C10C692D125833263894020|phrH]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK06839 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGCCAGACACATCATCACTT, downstream forward: _UP4_TAGGGCTTTTTCTTGCTTTAReferences