The second international online conference
#Subtillery2021 will be held 14th - 18th June - save the date, for more information see the
conference website!
The 21st
International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
yisQ
probable multidrug resistance protein
product
putative multidrug exporter
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.15|Multidrug exporters/ based on homology][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]Gene
Coordinates
1,160,776 1,162,143
The protein
Protein family
[SW|MOP exporter family][SW|multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family] (accordinig to UniProt)Structure
[PDB|3VVO] (MATE multidrug exporter from Pyrococcus furiosus, 23% identity) [pubmed|23535598][SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|5050D0049B87C9FF2ACCE45BD13FDA0227AAB804|yisQ]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-B182 (yisQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1181 NBRP B. subtilis, Japan]BKE10820 ([gene|5050D0049B87C9FF2ACCE45BD13FDA0227AAB804|yisQ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTGTCTAACCCCTTTC, downstream forward: _UP4_TAACACCCGGCTCAATCAAGBKK10820 ([gene|5050D0049B87C9FF2ACCE45BD13FDA0227AAB804|yisQ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTGTCTAACCCCTTTC, downstream forward: _UP4_TAACACCCGGCTCAATCAAGReferences