secreted protein of the WXG100 superfamily, homolog of virulence factor EsxA
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function][SW|Categories] containing this gene/protein
[SW|proteins of unknown function], [SW|most abundant proteins]This gene is a member of the following [SW|regulons]
[SW|DegU regulon]Gene
Coordinates on the chromosome (coding sequence)
3,276,141 -> 3,276,434
The protein
Protein family
WXG100 superfamily (pfam06013) [Pubmed|11973144][SW|Localization]
secreted, by the type VII [SW|protein secretion] system [protein|search|YukD]-[protein|search|YukC]-[protein|search|YukB]-[protein|search|YueB]-[protein|search|YueC] [Pubmed|24828531,23861817][SW|Interactions]
forms dimers [Pubmed|24828531,23861817]Expression and Regulation
Operon
''[protein|search|yukE]-[protein|search|yukD]-[protein|search|yukC]-[protein|search|yukB]-[protein|search|yueB]-[protein|search|yueC]'' [Pubmed|22383849,15576783][SW|Sigma factor]
[protein|search|SigA] [Pubmed|22383849]Regulation
not expressed in the lab strain 168, due to lack of [protein|search|DegU]-P [Pubmed|23861817]expressed in the stationary phase [Pubmed|23861817]Regulatory mechanism
[protein|search|DegU]-P: transcription activation [Pubmed|23861817]Additional information
belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]References
15576783,22383849,11973144,23861817,23861817,15378759,24798022,24696501,21395229,24828531 
