SubtiBank SubtiBank
secY
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

secY

preprotein translocase subunit, universally conserved protein
locus
BSU_01360
pI
10.21
mw
47.08 kDa
protein length
431 aa Sequence Blast
gene length
1296 bp Sequence Blast
function
protein secretion
product
preprotein translocase subunit
essential
yes
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins]

    • Gene

    Coordinates
    144,527 145,822

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • terminal phenotype of CRISPRi knockdown mutant is moderate bending and cessation of growth [Pubmed|27238023]

    • The protein

    Protein family

  • secY/SEC61-alpha family (single member, according to UniProt)

    • Structure

  • [PDB|3DL8] (structure of the ([protein|5350DC618130E013757EE667B9AFC5F2EC68EC08|SecY]-[protein|1007EA15FB7AF81A44400287DB68BCC497158ACF|SecE]-[protein|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|SecG])-[protein|AD7CD451B4AE638A719C91780339784A7FF0F248|SecA] complex [Pubmed|18923516]

    • [SW|Localization]

  • membrane [Pubmed|18763711]

    • Additional information

  • [SW|universally conserved protein]

    • Biological materials

    Mutant

  • Pspac-secY [Pubmed|8071801]
  • BEC01360, a CRISPRi knockdown mutant, is available from the [http://bgsc.org Bacillus Genetic Stock Center]

    • References

    Reviews

  • 25212246,27890920

    • Original publications

  • 27238023,2110998,12242434,8635744,23651456,18763711,8071801,8635744,18923516,23852076,26747607,27336478,21255212