SubtiBank SubtiBank
rnpB
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rnpB

RNA component of RNase P
locus
BSU_misc_RNA_35
pI
0.00
mw
0.00 kDa
function
cleavage of precursor sequences from the 5 ends of pre-tRNAs
product
RNA component of ribonuclease P (RNase P) (catalytic subunit, ribozyme)
essential
yes
synonyms
rnaP

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.4|RNases] → [category|SW 3.2.4.4|RNases/ Other]
  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.4|RNA component of RNase P]
  • Gene

    Phenotypes of a mutant

  • essential [Pubmed|23109554]
  • RNA

    Paralogous protein(s)

  • [[this]]
  • Structure

  • [PDB|3Q1R] (complex of [protein|594F2D36BE71A45303A33AA2A2931F56F0A969ED|RnpA] with [protein|57A79AAF00243B5E058FA901D43AA7B55CA33F63|RnpB] and [gene|3B6620F44EC08BA9B02FE9359A5F74C6CAE6D4FB|trnA-Ile], from ''Thermotoga maritima'') [Pubmed|21076397]
  • Labs working on this gene/protein

  • [SW|Carol Fierke], University of Michigan, Ann Arbor, USA [https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=fierke homepage]
  • [SW|Roland Hartmann], Marburg University, Germany [http://www.pharmazie.uni-marburg.de/pharmchem/akhartmann/ag_hartmann.htm homepage]
  • References

    Reviews

  • 19215776,17868095,14691942,16650980,16980936,16679018,14550630
  • Original Publications

  • 16470227,17355991,11812129,10390342,11454206,19549719,11454206,19717440,20133747,19932118,20188108,20434461,17299131,14510496,25402410,12951523,12836338,11577704,20557101,25352137,23109554,21076397,21622899,29116782,21076397