SAVE THE DATE! 21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.

ybaR

fumarate transporter

locus: BSU_01580

pI: 7.90

mw: 51.01 kDa

protein length: 478 aa

gene length: 1437 bp

function: uptake of fumarate

product: fumarate:proton symporter

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.4|Transporter for organic acids]
• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.1|Utilization of organic acids]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 177,083 178,519

The protein

Protein family

• SLC26A/SulP transporter (TC 2.A.53) family (with [protein|7028580E25DD6C1D49A14F29DDCC02012F94FED7|YvdB], according to UniProt)

[SW|Domains]

• [SW|STAS domain] (aa 389-478) (according to UniProt)

Structure

• [PDB|5DA0] (from ''Deinococcus radiodurans'', 63% identity) [Pubmed|26367249]

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|58B61B18D1C69BB9DCAB5EDFBFB3A498AA121386|ybaR]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-B948 (ybaR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1947 NBRP B. subtilis, Japan]
• BKE01580 ([gene|58B61B18D1C69BB9DCAB5EDFBFB3A498AA121386|ybaR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE01580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATATAACGACTCCTTTT, downstream forward: _UP4_TAAAATAGAGAAGCCCAGAT
• BKK01580 ([gene|58B61B18D1C69BB9DCAB5EDFBFB3A498AA121386|ybaR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK01580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATATAACGACTCCTTTT, downstream forward: _UP4_TAAAATAGAGAAGCCCAGAT

References

• 26367249