SubtiBank SubtiBank
gbsR

gbsR

transcription repressor of the gbsA-gbsB operon
locus
BSU31070
pI
4.62
mw
20.92 kDa
protein length
180 aa Sequence Blast
gene length
540 bp Sequence Blast
function
regulation of osmoprotection
product
transcription repressor
essential
no
synonyms
yuaC

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.4|Biosynthesis of glycine betaine]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress]
  • Gene

    Coordinates
    3,186,763 → 3,187,305

    The protein

    Catalyzed reaction/ biological activity

  • sensing of choline [Pubmed|22408163]
  • control of the ''[gene|1ADC55F8E265AF86E29743C671CE1EA1BE7EB41E|gbsA]-[gene|B90D4E798145F2AF3421DDC5AB6CD578E2E17900|gbsB]'' and ''[gene|3F502A4DCB1DAD7C3F968465B13C35213240515B|opuBA]-[gene|70B45E7428DB1F6AEF7D2FE3062CC86BE96674FC|opuBB]-[gene|C48798FE13B1521236F5BC5786B9A02D7BC9A336|opuBC]-[gene|1532EC3D741C5AB3D0B642741218FAE00AD460FA|opuBD]'' operons [Pubmed|22408163]
  • Effectors of protein activity

  • binds the inducer choline with an apparent K(D) of approximately 165 μM [Pubmed|22408163]
  • Biological materials

    Mutant

  • MGNA-A219 (yuaC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/219 NBRP B. subtilis, Japan]
  • Labs working on this gene/protein

  • [SW|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]
  • References

  • 22408163,28256787