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ftsA [2019-04-15 18:59:12]
cell division protein, membrane anchor for [protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ]
function
formation of Z-ring
product
[SW|cell division] protein
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
1,596,474 1,597,796
Phenotypes of a mutant
essential [Pubmed|28189581]cells become elongated [Pubmed|24218584]the ''[gene|672EA84D7725BE21F649DF30A11EB4E0EDFC3925|ftsA]'' mutation is synthetically lethal with a ''[gene|DB09F1C36257F511A84A083967A25A9D46744D14|sepF]'' mutation [Pubmed|24218584]The protein
Catalyzed reaction/ biological activity
required for septum recruitment of [protein|DF77B46666595E86081C5345C91E08F86DF9FAEE|SftA] [pubmed|29439991]Protein family
ftsA/mreB family (according to Swiss-Prot)Structure
[PDB|3WQT] (from Staphylococcus aureus, 31% identity) [pubmed|24746687][SW|Localization]
septal at the cell membrane (35% of the molecules) [Pubmed|29439991,20566861]cytoplasma (65% of the molecules) [pubmed|29439991]septal localization depends on the proton motive force [Pubmed|20566861]Biological materials
Mutant
1A787 ( ''ftsA''::''cat''), [Pubmed|8071208], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A787&Search=1A787 BGSC]References
Reviews
Original Publications
29439991,16796675,12081956,16159787,11298280,18776011,9287012,1569582,10878122,7592498,20566861,23036588,23701187,24218584,24224907,24316672,28189581,24746687 
