yflS [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

malate transporter

locus: BSU07570

pI: 9.74

mw: 51.00 kDa

function: malate uptake

product: malate transporter

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.4|Transporter for organic acids]
• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.1|Utilization of organic acids]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|utilization of specific carbon sources], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|MalR regulon]

Gene

Coordinates on the chromosome (coding sequence): 829,382 -> 830,818

The protein

Protein family

• View classification (according to Swiss-Prot)

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|yflS]'' [Pubmed|21815947]

Regulation

• induced by malate ([protein|search|MalR])

Regulatory mechanism

• [protein|search|MalR]: transcription activation

Additional information

• the mRNA is substantially stabilized upon depletion of [Rny|search|RNase Y] [PubMed|21815947]

Biological materials

Mutant

• GP1450 (cat), available in [SW|Jörg Stülke]'s lab

References

• 12949159,21815947