The papers of the month are back! Check them out! Link here

pncB

putative nicotinate phosphoribosyltransferase

locus: BSU31750

pI: 5.09

mw: 56.01 kDa

protein length: 490 aa

gene length: 1470 bp

function: unknown

product: putative nicotinate phosphoribosyltransferase

essential: yes

ec: 2.4.2.11

synonyms: yueK

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
• [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

Gene

Coordinates: 3,259,403 → 3,260,875

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)

Protein family

• NAPRTase family (according to Swiss-Prot)

Structure

• [PDB|2F7F] (from ''Enterococcus faecalis'', 61% identity)

Expression and Regulation

Operons

• genes: [gene|7CA7ADDBDDE46B0E6522704FD19C0BCF6FA9E058|pncB]
  description: [Pubmed|9274030]

Biological materials

Mutant

• MGNA-B562 (yueK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1561 NBRP B. subtilis, Japan]

References

• 16199587,9274030