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motA [Mon Aug 31 2015 13:53:57 GMT+0200 (CEST)]
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motA [Mon Aug 31 2015 13:53:57 GMT+0200 (CEST)]

H+-coupled MotA-MotB flagellar stator
locus
BSU13690
pI
5.01
mw
29.00 kDa
function
motility and chemotaxis
product
motility protein (flagellar motor rotation)
essential
no
synonyms
mot

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.6|Other proteins required for efficient pellicle biofilm formation]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • syns
    mot

    [SW|Categories] containing this gene/protein

  • [SW|motility and chemotaxis], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigD regulon]
  • Gene

    Phenotypes of a mutant

  • loss of swimming and swarming motility [Pubmed|24296669]
  • mucoid phenotype due to the [protein|search|DegU]-P activated overexpression of the ''[protein|search|capB]-[protein|search|capC]-[protein|search|capA]-[protein|search|capE]'' operon and resulting overproduction of poly-gamma-glutamate [Pubmed|24296669]
  • not essential for pellicle biofilm formation, but mutant is outcompeted by the wild-type strain when competed during pellicle formation [Pubmed|26122431]
  • The protein

    Protein family

  • motA family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|MotP]
  • Effectors of protein activity

  • the interaction with [protein|search|DgrA] inhibits [protein|search|MotA] activity [Pubmed|22821967]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|MotA]-[protein|search|MotB]
  • [protein|search|DgrA]-[protein|search|MotA] [Pubmed|22821967]
  • Expression and Regulation

    Operon

  • ''[protein|search|motA]-[protein|search|motB]'' [Pubmed|6313226]
  • [SW|Sigma factor]

  • [protein|search|SigD] [Pubmed|6313226]
  • Biological materials

    Mutant

  • 1A631 ( ''motA''::''erm''), [Pubmed|3015878], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A631&Search=1A631 BGSC]
  • 1A923 ( ''motA''::''erm''), [Pubmed|12813063], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A923&Search=1A923 BGSC]
  • DS7498 (marker-less in NCIB3610) [Pubmed|24296669]
  • References

  • 26122431,6313226,21821766,22821967,24296669,24771657