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motA [2017-8-11 16:0:3]
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motA [2017-8-11 16:0:3]

H+-coupled MotA-MotB flagellar stator
locus
BSU13690
pI
5.01
mw
29.19 kDa
protein length
270 aa Sequence Blast
gene length
810 bp Sequence Blast
function
motility and chemotaxis
product
motility protein (flagellar motor rotation)
essential
no
synonyms
mot
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.6|Other proteins required for efficient pellicle biofilm formation]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,434,433 → 1,435,245

    Phenotypes of a mutant

  • loss of swimming and swarming motility [Pubmed|24296669]
  • mucoid phenotype due to the [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU]-P activated overexpression of the ''[gene|86C05126ADBA22BB1771B1FA3D214B2E7A36311E|capB]-[gene|D66994D077D1382B88FF65075E44C2A31089548F|capC]-[gene|A696434A086A428D411CAF45B37CD8F82AC2503F|capA]-[gene|6B61DCE8D27776EBF942621D3AE90F410FD13F37|capE]'' operon and resulting overproduction of poly-gamma-glutamate [Pubmed|24296669]
  • not essential for pellicle biofilm formation, but mutant is outcompeted by the wild-type strain when competed during pellicle formation [Pubmed|26122431]

    • The protein

    Protein family

  • motA family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|3D42584D65D80A1C73F057714647E29FF6BBD58A|MotP]

    • Effectors of protein activity

  • the interaction with [protein|C194336ED96FA844FFE9FB43BE59ADC5D6DDB3BE|MotI] inhibits [protein|86C729C7D5ABEE519ADC4A893940600BBB655EF1|MotA] activity [Pubmed|22821967]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Biological materials

    Mutant

  • 1A631 ( ''motA''::''erm''), [Pubmed|3015878], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A631&Search=1A631 BGSC]
  • 1A923 ( ''motA''::''erm''), [Pubmed|12813063], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A923&Search=1A923 BGSC]
  • DS7498 (marker-less in NCIB3610) [Pubmed|24296669]

    • References

  • 26122431,6313226,21821766,22821967,24296669,24771657,28378843