SubtiBank SubtiBank
ytxJ
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ytxJ

general stress protein, putative bacillredoxin
locus
BSU_29760
pI
5.09
mw
12.26 kDa
protein length
108 aa Sequence Blast
gene length
327 bp Sequence Blast
function
unknown
product
putative bacillredoxin
essential
no
synonyms
csb40

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.8|Phosphorylation on either a Ser, Thr or Tyr residue]
  • Gene

    Coordinates
    3,046,757 3,047,083

    The protein

    Protein family

  • Trx family
  • [SW|Domains]

  • contains a single conserved Cys residue in a motif (TCPIS) reminiscent of that found in monothiol glutaredoxins [Pubmed|20308541]
  • Modification

  • phosphorylation on (Thr-93 OR Ser-94 OR Ser-96 OR Thr-99) [Pubmed|17218307]
  • Structure

  • [PDB|3IV4] (from Staphylococcus aureus, 41% identity)
  • Expression and Regulation

    Operons

    genes
    [gene|00A42FDB559BE2647CD682180420A435E2E7035F|ytxG]-[gene|43BF293F735ED783D36F33AA4701D57F2AED6657|ytxH]-[gene|8B4E1D087B75B5E77BCB60FF3465270CEB72B028|ytxJ]
    description
    [Pubmed|8733232]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|8733232,11544224], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • [protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH]: sigma factor, [Pubmed|8733232], in [regulon|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH regulon]
  • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|8733232,11544224]
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    Biological materials

    Mutant

  • MGNA-B527 (ytxJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1526 NBRP B. subtilis, Japan]
  • BKE29760 ([gene|8B4E1D087B75B5E77BCB60FF3465270CEB72B028|ytxJ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTCAAGCTCTTCCTT, downstream forward: _UP4_TAGAAAAAAGCGTCCAGATA
  • BKK29760 ([gene|8B4E1D087B75B5E77BCB60FF3465270CEB72B028|ytxJ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTCAAGCTCTTCCTT, downstream forward: _UP4_TAGAAAAAAGCGTCCAGATA
  • References

  • 11544224,17218307,8733232,20308541