SubtiBank SubtiBank
alsR

alsR

transcriptional activator of the alsS-alsD operon
locus
BSU36020
pI
7.29
mw
34.18 kDa
protein length
302 aa Sequence Blast
gene length
906 bp Sequence Blast
function
regulation of acetoin synthesis (alsS-alsD)
product
transcriptional activator(LysR family)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.1|Carbon core metabolism] → [category|SW 2.2.1.5|Overflow metabolism]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • Gene

    Coordinates
    3,711,498 → 3,712,406

    Phenotypes of a mutant

  • no acetoin production
  • The protein

    Catalyzed reaction/ biological activity

  • binds the promoter region of the ''[gene|AAA45830B9C5428CADFA5551D33B513E9B1B7C8E|alsS]-[gene|355E70F55A28C6C2C24E8E326EFB673AC303FBEE|alsD]'' operon in the presence of acetate, activates transcription
  • Protein family

  • [SW|LysR family] of transcription factors
  • Biological materials

    Mutant

  • AMBs3 (spc), available in the [SW|Stülke] lab
  • 1A978 ( ''alsR''::''cat''), [Pubmed|7685336], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A978&Search=1A978 BGSC]
  • Labs working on this gene/protein

  • [SW|Elisabeth Härtig], Braunschweig, Germany [http://www.tu-braunschweig.de/ifm/abt/jahn/groups/bs Homepage]
  • References

    Reviews

  • 23046954
  • Original publications

  • 7685336,21821766,22344650,23576037,22178965,23695583,23836140