The second international online conference
#Subtillery2021 will be held 14th - 18th June - save the date, for more information see the
conference website!
The 21st
International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
yhdR
similar to aspartate aminotransferase
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
1,034,046 1,035,227
The protein
Catalyzed reaction/ biological activity
2-oxoglutarate + L-aspartate --> L-glutamate + oxaloacetate (according to UniProt)Protein family
[SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to UniProt)[SW|Cofactors]
PLPStructure
[PDB|3ELE] (from Eubacterium rectale, 34% identity)[SW|Localization]
cytoplasm (according to Swiss-Prot)Additional information
The gene is annotated in KEGG as aspartate aminotransferase EC 2.6.1.1. In MetaCyc the protein is marked as similar to aspartate aminotransferase. No EC annotation is available in Swiss-Prot. No literature/experimental evidence supporting the annotation is availablavailable. [Pubmed|19935659]Expression and Regulation
Operons
genes
[gene|8F7432F7EF0F767C6000D553A3ACE29FBA2EDCEE|yhdR]
description
[Pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-B485 (yhdR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1484 NBRP B. subtilis, Japan]BKE09570 ([gene|8F7432F7EF0F767C6000D553A3ACE29FBA2EDCEE|yhdR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTGTCCCTTCCGCATAT, downstream forward: _UP4_TAAGAAGGCAAAGAAAAGAABKK09570 ([gene|8F7432F7EF0F767C6000D553A3ACE29FBA2EDCEE|yhdR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTGTCCCTTCCGCATAT, downstream forward: _UP4_TAAGAAGGCAAAGAAAAGAA