SubtiBank SubtiBank
spoIIID

spoIIID

transcriptional regulator (repressor or activator) of a subset of sigma-E-dependent genes
locus
BSU36420
pI
9.50
mw
10.66 kDa
protein length
gene length
279 bp Sequence Blast
function
regulation of mother cell gene expression
product
transcriptional regulator
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • Gene

    Coordinates
    3,748,421 → 3,748,702

    The protein

    Catalyzed reaction/ biological activity

  • binds its DNA targets as a monomeric protein (possible due to the two DNA-binding motifs) [Pubmed|20061473]
  • [SW|Domains]

  • two DNA-binding regions: HTH at the N-terminus and a basic region near the C-terminus [Pubmed|20061473]
  • Structure

  • [PDB|2L0K] (complex with DNA)
  • Expression and Regulation

    Operons

    genes
    [gene|487990143C84D245743C0014E648699627204FF0|usd]-[gene|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]-[gene|6ED386D49F973C1F6B1076974F54275DD583C9D3|mbl]
    description
    [Pubmed|22383849]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|9023218], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]
  • regulation

  • expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|9023218]
  • additional information

  • An [ncRNA|search|antisense RNA] is predicted for '[protein|search|mbl]' [PubMed|20525796]
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    References

  • 15383836,1469717,7896717,1900494,8231808,9023218,2112673,1691789,10788508,1744038,7966271,2514119,1518043,17693505,9006059,20061473,17890309,17693499,7836311,24584501,22463703