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yaaI
general stress protein, similar to isochorismatase
function
survival of ethanol stress
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
25,221 25,766
The protein
Protein family
[SW|Isochorismatase family] (according to UniProt)Structure
[PDB|3TG2] (from Vibrio cholerae, 26% identity) [pubmed|22993087]Additional information
important for survival of ethanol stress [Pubmed|15805528]Expression and Regulation
Operons
genes
[gene|95C78F511C49E04241D31593E6837BDFF48D6E14|yaaI]-[gene|77BEC74867422AA225A1F12AD63464656DBDCBE8|yaaH]
description
[pubmed|22383849]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]regulation
induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]) [Pubmed|15805528]view in new tabBiological materials
Mutant
MGNA-B890 (yaaI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1889 NBRP B. subtilis, Japan]BKE00170 ([gene|95C78F511C49E04241D31593E6837BDFF48D6E14|yaaI]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE00170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATCGACAGTCTCCTTTCC, downstream forward: _UP4_TAAACATGATCAGCGCTTTTBKK00170 ([gene|95C78F511C49E04241D31593E6837BDFF48D6E14|yaaI]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK00170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATCGACAGTCTCCTTTCC, downstream forward: _UP4_TAAACATGATCAGCGCTTTTReferences
15805528,15805528,22993087