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yugU
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yugU

general stress protein, survival of ethanol and paraquat stresses
locus
BSU_31280
pI
6.59
mw
16.17 kDa
protein length
132 aa Sequence Blast
gene length
399 bp Sequence Blast
function
survival of stress conditions
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

    • Gene

    Coordinates
    3,213,854 3,214,252

    The protein

    Protein family

  • UPF0047 family (single member, according to UniProt)

    • Structure

  • [PDB|1VMH] (the protein from ''Clostridium acetobutylicum'', 54% identity, 83% similarity)

    • Expression and Regulation

    Operons

    genes
    [gene|A4BF42889C55566ACE702561E34109F184413B85|yugU]-[gene|561B400C0255AAC2B52ADBBCA05D373E6366CD40|yuzH]
    description
    [pubmed|22383849]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|26577401], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15383836], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

    • regulatory mechanism

  • [protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID]: repression, [Pubmed|15383836], in [regulon|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID regulon]
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    Biological materials

    Mutant

  • MGNA-A616 (yugU::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/616 NBRP B. subtilis, Japan]
  • BKE31280 ([gene|A4BF42889C55566ACE702561E34109F184413B85|yugU]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE31280 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGTTTCTCCTTTCGTT, downstream forward: _UP4_TAATAGGCTGTTTTTTATGA
  • BKK31280 ([gene|A4BF42889C55566ACE702561E34109F184413B85|yugU]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK31280 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGTTTCTCCTTTCGTT, downstream forward: _UP4_TAATAGGCTGTTTTTTATGA

    • References

  • 15805528,22582280