SAVE THE DATE! 21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.

yxbC

unknown

locus: BSU_39880

pI: 4.59

mw: 37.30 kDa

protein length: 330 aa

gene length: 993 bp

function: unknown

product: unknown

essential: no

synonyms: yxaQ

Genomic Context

categories

• [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

Gene

Coordinates: 4,095,915 4,096,907

The protein

Protein family

• ROX family (single member, according to UniProt)

[SW|Domains]

• JmjC domain (aa 96-256) (according to UniProt)

Structure

• [PDB|1VRB]

Expression and Regulation

Operons

• genes: [gene|A9815CF5DA9D8852F387DAF94CC26E95F1E4AC25|yxbC]-[gene|4DB53AE08A4E4841D0411A5590CC09A6ECC8E74E|yxbD]
  description: [Pubmed|10746760]

  regulatory mechanism

  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: activation, [Pubmed|14651647], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon]
  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [Pubmed|12618455], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|15101989], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

  regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]

Biological materials

Mutant

• MGNA-B691 (yxbC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1690 NBRP B. subtilis, Japan]
• BKE39880 ([gene|A9815CF5DA9D8852F387DAF94CC26E95F1E4AC25|yxbC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTATCCCTCCCAAAAA, downstream forward: _UP4_TAGTAAATACTAGATAAGGG
• BKK39880 ([gene|A9815CF5DA9D8852F387DAF94CC26E95F1E4AC25|yxbC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTATCCCTCCCAAAAA, downstream forward: _UP4_TAGTAAATACTAGATAAGGG

References

• 10746760,18083814,12618455,14651647,12618455,15101989