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dnaI

[SW|primosome] component (helicase loader), part of the [SW|replisome]

locus: BSU_28980

pI: 5.74

mw: 35.96 kDa

protein length: 311 aa

gene length: 936 bp

function: [category|SW 3.1.1|DNA replication]

product: [SW|primosome] component (helicase loader)

essential: yes

synonyms: ytxA,dnaY

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

Gene

Coordinates: 2,963,185 2,964,120

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Structure

• [PDB|2K7R] (N-terminal domain)
• [PDB|4M4W] (the [protein|5CF09E089AA70A32F640CE0D33D1F05312AAE24D|DnaC]-[protein|AC1B507C6B1640E9BEA1F9F01628120F3680C976|DnaI]-[protein|F7B53E8AC92DAD15544C6208C2A5B41BABA73D6D|DnaG] complex) [Pubmed|24048025]

[SW|Localization]

• cell membrane (according to Swiss-Prot), Cytoplasm (Homogeneous) [Pubmed|16479537] forms foci, close to oriC [Pubmed|10844689]

Expression and Regulation

Operons

• genes: [gene|2AEF6D56D884CA6A0BD50FABD27F405DC2B506C7|dnaB]-[gene|AC1B507C6B1640E9BEA1F9F01628120F3680C976|dnaI]-[gene|72A4458679EA1451FA3B63D44C3BE93ACA8B397F|ytxB]-[gene|3EE0D03469D893515CAA4961BF923BE3A6769535|ytxC]-[gene|3E1131CFA3EDEB3865638F09BE2F6B6ED2570BE2|thrS]
  description: [Pubmed|22383849]

References

Reviews

• 22797751,28075389

Original publications

• 19255093,10844689,12718886,11842108,20122408,16479537,19744498,19255093,19968790,11679082,24048025,30285297