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glvR
transcriptional activator of the [gene|C650160C9E5B5F8587CA9E80A57BCCE97D701037|malA]-[gene|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]-[gene|E6C7733A12AF9A5322EED444E4A4FF1605A8B20F|malP] operon
function
regulation of maltose utilization
product
transcriptional activator
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.22|Utilization of maltose][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]Gene
Coordinates
891,436 892,200
The protein
[SW|Domains]
HTH rpiR-type domain (aa 1-77) (according to UniProt)[SW|SIS domain] (aa 106-248) (according to UniProt)Expression and Regulation
Operons
genes
[gene|C650160C9E5B5F8587CA9E80A57BCCE97D701037|malA]-[gene|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]-[gene|E6C7733A12AF9A5322EED444E4A4FF1605A8B20F|malP]
description
[Pubmed|11489864]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|11489864], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|AD72489DA260F07B97A213F1F0FBA7CED9471817|GlvR]: activation, [Pubmed|11489864], in [regulon|AD72489DA260F07B97A213F1F0FBA7CED9471817|GlvR regulon][protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|11489864], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]regulation
induction by maltose ([protein|search|GlvR]) [Pubmed|11489864]view in new tabBiological materials
Mutant
MGNA-C290 (yfiA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2288 NBRP B. subtilis, Japan]BKE08190 ([gene|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08190 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCAGATCCCCCCATTT, downstream forward: _UP4_AATGACAATGAGTAGCAGGGGBKK08190 ([gene|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08190 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCAGATCCCCCCATTT, downstream forward: _UP4_AATGACAATGAGTAGCAGGGGReferences