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coaA [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]
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coaA [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

type I pantothenate kinase, major enzyme
locus
BSU23760
pI
5.89
mw
36.00 kDa
function
biosynthesis of coenzyme A
product
pantothenate kinase
essential
no
ec
2.7.1.33
synonyms
yqjS
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.4|Biosynthesis of coenzyme A]

    • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of cofactors]

    • Gene

    Coordinates on the chromosome (coding sequence)
    2,468,549 -> 2,469,508

    The protein

    Catalyzed reaction/ biological activity

  • ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate (according to Swiss-Prot)

    • Protein family

  • prokaryotic pantothenate kinase family (according to Swiss-Prot)

    • Structure

  • [PDB|1SQ5] (from ''Escherichia coli'', 49% identity, 67% similarity) [Pubmed|15136582]

    • Expression and Regulation

    Operon

  • ''[protein|search|yqjP]-[protein|search|yqjQ]-[protein|search|dsdA]-[protein|search|coaA]-[protein|search|yqjT]'' (according to [http://dbtbs.hgc.jp/COG/prom/yqjPQ-dsdA-coaA-yqjT.html DBTBS])

    • References

  • 1328157,24784177