SubtiBank SubtiBank
arsR
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arsR

transcriptional regulator of the [SW|ArsR family], arsenic resistance operon repressor
locus
BSU_25810
pI
4.88
mw
12.15 kDa
protein length
105 aa Sequence Blast
gene length
318 bp Sequence Blast
function
regulation of As (III) efflux
product
transcription repressor ([SW|ArsR family])
essential
no
synonyms
yqcJ

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.11|Resistance against toxic metals]
  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.3|Skin element]
  • Gene

    Coordinates
    2,657,317 → 2,657,634

    The protein

    Protein family

  • [SW|ArsR family]
  • Structure

  • [PDB|1U2W] (CadC from Staphylococcus aureus, 36% identity) [pubmed|15937183]
  • Expression and Regulation

    Operons

    genes
    [gene|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR]-[gene|74B1AF103E6B236609CD184A1A409A9A04857181|yqcK]-[gene|B749D54249A28A471EF796903A34622A16D5B0BB|arsB]-[gene|DB3527FB78D0B7C144D1699D665788184F19AFE0|arsC]
    description
    [Pubmed|9537360]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|9537360], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF]: sigma factor, [Pubmed|16497325], in [regulon|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF regulon]
  • regulatory mechanism

  • [protein|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|ArsR]: repression, [Pubmed|9537360], in [regulon|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|ArsR regulon]
  • regulation

  • expressed early during sporulation in the forespore ([protein|search|SigF]) [Pubmed|16497325]
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    Biological materials

    Mutant

  • BKE25810 (Δ[gene|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE25810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCATATCGCCTTCTTTA, downstream forward: _UP4_TAAAAAAATTTTTTAGGTAT
  • BKK25810 (Δ[gene|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK25810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCATATCGCCTTCTTTA, downstream forward: _UP4_TAAAAAAATTTTTTAGGTAT
  • References

  • 15948947,9537360,16497325,15937183