yfkF

similar to multidrug-efflux transporter

locus: BSU_07910

pI: 8.91

mw: 42.53 kDa

protein length: 391 aa

gene length: 1176 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.12|Other transporters]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 863,862 → 865,037

The protein

Protein family

• [SW|major facilitator superfamily] (according to UniProt)

Structure

• [PDB|3WDO] (from E. coli, corresponds to aa 233 ... 344, 26% identity) [pubmed|23950222]

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|B56B38A1CCC0A73FFD9F3F4C9942356E6D818D2D|yfkF]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-C347 (yfkF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2345 NBRP B. subtilis, Japan]
• BKE07910 (Δ[gene|B56B38A1CCC0A73FFD9F3F4C9942356E6D818D2D|yfkF]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE07910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTGTCAGTTCTCCTTA, downstream forward: _UP4_TAATCAAAAAGCCTCCCGAC
• BKK07910 (Δ[gene|B56B38A1CCC0A73FFD9F3F4C9942356E6D818D2D|yfkF]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK07910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTGTCAGTTCTCCTTA, downstream forward: _UP4_TAATCAAAAAGCCTCCCGAC

References

• 26528249,23950222