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ywpB

?-hydroxyacyl-(acyl carrier protein) dehydratase

locus: BSU36370

pI: 9.36

mw: 14.63 kDa

protein length: 132 aa

gene length: 396 bp

function: fatty acid biosynthesis

product: β-hydroxyacyl-ACP dehydratase

essential: yes

ec: 4.2.1.59

synonyms: fabZ

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.1|Biosynthesis of fatty acids]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

Gene

Coordinates: 3,743,732 → 3,744,157

Phenotypes of a mutant

• essential [Pubmed|23109554]

The protein

Protein family

• FabZ subfamily (according to Swiss-Prot)

Paralogous protein(s)

• [protein|65506215AE58BF53C57599E566E4F78514DB45AA|YcsD]

Structure

• [PDB|3D6X] (from ''Campylobacter jejuni'', 45% identity, 67% similarity) [Pubmed|19280690]

Biological materials

Mutant

• MGNA-B265 (ywpB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1264 NBRP B. subtilis, Japan]

References

• 17919287,19280690