yhdP [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

potential magnesium efflux pump, mutation suppresses defects in 70 S ribosome formation

locus: BSU09550

pI: 4.00

mw: 49.00 kDa

function: export of magnesium

product: potential magnesium efflux pump

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.1|Magnesium uptake/ efflux]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|metal ion homeostasis (K, Na, Ca, Mg)], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 1,032,063 -> 1,033,397

The protein

Protein family

• UPF0053 family (according to Swiss-Prot)

Paralogous protein(s)

• [SW|YhdT], [SW|YrkA], [SW|YqhB], [SW|YugS]

[SW|Domains]

• [SW|DUF21 domain] (5-201)
• 2 [SW|CBS domain]s (220-282, 284-344)

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|cueR]-[protein|search|yhdP]'' [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A696 (yhdP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/696 NBRP B. subtilis, Japan]

Expression vector

• pGP2931 (N-terminal His-tag, purification from ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s lab

References

• 10960106,22383849,25182490