pps

similar to rifampicin phosphotransferase

locus: BSU_18830

pI: 5.29

mw: 97.00 kDa

protein length: 866 aa

gene length: 2601 bp

function: resistance to rifampicin

product: similar to rifampicin phosphotransferase

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]

Gene

Coordinates: 2,051,329 → 2,053,929

The protein

Protein family

• [SW|PEP-utilizing enzyme family] (according to UniProt)

Paralogous protein(s)

• [protein|7235F9D0048961BBD93FA6A4322018029A607435|YvkC]

Structure

• [PDB|5HV1] (from ''Listeria monocytogenes'', 62% identity) [pubmed|27001859]

Additional information

• The gene is annotated in KEGG and MetaCyc as phosphoenolpyruvate synthase EC 2.7.9.2. In Swiss-Prot the protein is described as “phosphoenolpyruvate synthase”. No literature/experimental evidence supporting the annotation is available. [Pubmed|19935659]

Expression and Regulation

Operons

• genes: [gene|BF0329D469211F579F5CF0CBB58A6D96DD8CB839|pps]
  description: [Pubmed|22383849]

Biological materials

Mutant

• BKE18830 (Δ[gene|BF0329D469211F579F5CF0CBB58A6D96DD8CB839|pps]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTACATCTCCCCTTCA, downstream forward: _UP4_TAATGTCTGATGTGTGTAGA
• BKK18830 (Δ[gene|BF0329D469211F579F5CF0CBB58A6D96DD8CB839|pps]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTACATCTCCCCTTCA, downstream forward: _UP4_TAATGTCTGATGTGTGTAGA

References

• 19935659,20525796,27001859