SubtiBank SubtiBank
bceR

bceR

two-component response regulator (OmpR family), regulation of bceA-bceB in response to external (bacitracin, plectasin, mersacidin and actagardine) and internal (SdpC, SkfA) antimicrobial peptides
locus
BSU30400
pI
5.29
mw
26.72 kDa
protein length
231 aa Sequence Blast
gene length
693 bp Sequence Blast
function
resistance against toxic peptides
product
two-component response regulator (OmpR family)
essential
no
synonyms
ytsA

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.1|Two-component system response regulators]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue]
  • Gene

    Coordinates
    3,113,187 → 3,113,882

    The protein

    Protein family

  • [SW|OmpR family]
  • Modification

  • phosphorylated by [protein|08F24CA21DC54031F6158AC0C772F3B520E5A849|BceS] on an Asp residue
  • Structure

  • [PDB|1KGS] (DrrD from ''Thermotoga maritima '', 32% identity) [Pubmed|11839301]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    genes
    [gene|C239C155F5452C86BF6C78190BABBBB07A63DF87|bceR]-[gene|08F24CA21DC54031F6158AC0C772F3B520E5A849|bceS]
    description
    [Pubmed|12399481]
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    Biological materials

    Mutant

  • MGNA-A133 (ytsA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/133 NBRP B. subtilis, Japan]
  • References

    Reviews

  • 27344142,28152228
  • Original publications

  • 10094672,18394148,12890034,14651641,21283517,20606066,17905982,25118291,22964256,21078927,26199330,26364265,11839301,27997719