SubtiBank SubtiBank
yngA
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yngA

unknown
locus
BSU_18170
pI
9.15
mw
16.52 kDa
protein length
148 aa Sequence Blast
gene length
447 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]
  • Gene

    Coordinates
    1,946,249 → 1,946,695

    The protein

    Protein family

  • GtrA family (with [protein|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|GtcA], according to UniProt)
  • Structure

  • [PDB|5MLZ] (from Pyrococcus furiosus, 20% identity) [pubmed|28743912]
  • [SW|Localization]

  • cell membrane (according to UniProt)
  • Expression and Regulation

    Operons

    genes
    [gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]-[gene|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB]-[gene|289828D37CF5422908316ED2EF1AEAE76F84161D|yngC]
    description
    [Pubmed|20512483]

    sigma factors

  • [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]
  • regulatory mechanism

  • [protein|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ]: activation, [Pubmed|20512483], in [regulon|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ regulon]
  • regulation

  • expression during spore [SW|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]
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    Biological materials

    Mutant

  • MGNA-B395 (yngA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1394 NBRP B. subtilis, Japan]
  • BKE18170 (Δ[gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTTGTTGATATGGATT, downstream forward: _UP4_ATACAGGATCAGGAGTGAAG
  • BKK18170 (Δ[gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTTGTTGATATGGATT, downstream forward: _UP4_ATACAGGATCAGGAGTGAAG
  • References

  • 20512483,27766092,28743912