The second international online conference
#Subtillery2021 will be held 14th - 18th June - save the date, for more information see the
conference website!
The 21st
International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
yngA
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]Gene
Coordinates
1,946,249 → 1,946,695
The protein
Protein family
GtrA family (with [protein|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|GtcA], according to UniProt)Structure
[PDB|5MLZ] (from Pyrococcus furiosus, 20% identity) [pubmed|28743912][SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]-[gene|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB]-[gene|289828D37CF5422908316ED2EF1AEAE76F84161D|yngC]
description
[Pubmed|20512483]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]regulatory mechanism
[protein|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ]: activation, [Pubmed|20512483], in [regulon|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ regulon]regulation
expression during spore [SW|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]view in new tabBiological materials
Mutant
MGNA-B395 (yngA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1394 NBRP B. subtilis, Japan]BKE18170 (Δ[gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTTGTTGATATGGATT, downstream forward: _UP4_ATACAGGATCAGGAGTGAAGBKK18170 (Δ[gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTTGTTGATATGGATT, downstream forward: _UP4_ATACAGGATCAGGAGTGAAGReferences
20512483,27766092,28743912