SubtiBank SubtiBank
yngA
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yngA

unknown
locus
BSU_18170
pI
9.15
mw
16.52 kDa
protein length
148 aa Sequence Blast
gene length
447 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

    • Gene

    Coordinates
    1,946,249 → 1,946,695

    The protein

    Protein family

  • GtrA family (with [protein|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|GtcA], according to UniProt)

    • Structure

  • [PDB|5MLZ] (from Pyrococcus furiosus, 20% identity) [pubmed|28743912]

    • [SW|Localization]

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]-[gene|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB]-[gene|289828D37CF5422908316ED2EF1AEAE76F84161D|yngC]
    description
    [Pubmed|20512483]

    sigma factors

  • [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]

    • regulatory mechanism

  • [protein|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ]: activation, [Pubmed|20512483], in [regulon|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ regulon]

    • regulation

  • expression during spore [SW|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]
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    Biological materials

    Mutant

  • MGNA-B395 (yngA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1394 NBRP B. subtilis, Japan]
  • BKE18170 (Δ[gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTTGTTGATATGGATT, downstream forward: _UP4_ATACAGGATCAGGAGTGAAG
  • BKK18170 (Δ[gene|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTTGTTGATATGGATT, downstream forward: _UP4_ATACAGGATCAGGAGTGAAG

    • References

  • 20512483,27766092,28743912