SubtiBank SubtiBank
holA
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holA

DNA polymerase III, delta subunit, part of the clamp-loader complex and the [SW|replisome]
locus
BSU_25560
pI
6.23
mw
40.35 kDa
protein length
347 aa Sequence Blast
gene length
1044 bp Sequence Blast
function
[category|SW 3.1.1|DNA replication]
product
DNA polymerase III, delta subunit
essential
yes
ec
2.7.7.7
synonyms
yqeN

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • Gene

    Coordinates
    2,636,096 → 2,637,139

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Catalyzed reaction/ biological activity

  • required for bacteriophage SPP1 replication [Pubmed|23268446]
  • [SW|Domains]

  • domain I: aa 1 - 143, RecA-like fold [Pubmed|23525462]
  • domain II: aa 144 - 214, four alpha helices [Pubmed|23525462]
  • domain III: aa 215 - 339, seven alpha helices [Pubmed|23525462]
  • Structure

  • [PDB|3ZH9] [Pubmed|23525462]
  • [SW|Localization]

  • Nucleoid (Mid-cell) [Pubmed|16479537]
  • Expression and Regulation

    Operons

    genes
    [gene|CE70B471811371D454A74F67279974BF264205C2|holA]
    description
    [Pubmed|22383849]
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    References

  • 16479537,20122408,23525462,23268446,23563155