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yycA

unknown

locus: BSU_40490

pI: 9.68

mw: 73.41 kDa

protein length: 685 aa

gene length: 2058 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

Gene

Coordinates: 4,161,103 → 4,163,160

The protein

Protein family

• glycosyltransferase 39 family (with [protein|7039FCF49F97FFEF37ED48D6F860E3873A5CF308|YkcB], according to UniProt)

Paralogous protein(s)

• [protein|7039FCF49F97FFEF37ED48D6F860E3873A5CF308|YkcB]

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|1CB229DE87D56674903A8348657FA3B3117FEADD|yycC]-[gene|00F319EEC8420F859BA2657B9D4D1281853A94BD|yycB]-[gene|CFEA05E10517C00222126F959A1D2DCE7604E478|yycA]
  description: [Pubmed|22383849]

  regulatory mechanism

  • [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]: repression, [Pubmed|12823818], in [regulon|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA regulon]

  regulation

  • repressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]) [Pubmed|12823818]

• genes: [gene|CFEA05E10517C00222126F959A1D2DCE7604E478|yycA]
  description: [pubmed|22383849]

  regulatory mechanism

  • [protein|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ]: activation, [Pubmed|20512483], in [regulon|706983E6942E883D3A9D45693E7B4015AEABE60B|YclJ regulon]

Biological materials

Mutant

• MGNA-B833 (yycA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1832 NBRP B. subtilis, Japan]
• BKE40490 (Δ[gene|CFEA05E10517C00222126F959A1D2DCE7604E478|yycA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE40490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTTTTTCACCTCTTTA, downstream forward: _UP4_TAAAAAAAGAGGCTTGGATG
• BKK40490 (Δ[gene|CFEA05E10517C00222126F959A1D2DCE7604E478|yycA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK40490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTTTTTCACCTCTTTA, downstream forward: _UP4_TAAAAAAAGAGGCTTGGATG

References

• 20512483