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gcvPA [2017-8-11 16:0:3]
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gcvPA [2017-8-11 16:0:3]

glycine decarboxylase (subunit 1)
locus
BSU24560
pI
6.95
mw
49.33 kDa
protein length
448 aa Sequence Blast
gene length
1344 bp Sequence Blast
function
glycine utilization
product
glycine decarboxylase (subunit 1)
essential
no
ec
1.4.4.2
synonyms
yqhJ, gcvP

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.8|Utilization of threonine/ glycine]
  • Gene

    Coordinates
    2,546,869 → 2,548,215

    The protein

    Catalyzed reaction/ biological activity

  • Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2 (according to Swiss-Prot)
  • Protein family

  • N-terminal subunit subfamily (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    genes
    [gene|F6F449170276055E6D60D89E9E17A152A82CA166|gcvT]-[gene|DB0618EBA12013842ED3972165D0276F438D8EC1|gcvPA]-[gene|20175DF9FCF07C34A05C572B089C33D1E1FE6DF2|gcvPB]
    description
    [Pubmed|15472076]

    regulatory mechanism

  • [regulon|Gly-box|Gly-box]: termination, [pubmed|31992591], in [regulon|Gly-box|Gly-box]
  • regulation

  • induced by glycine [Pubmed|15472076]
  • the [SW|Gly-box] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]
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    Biological materials

    Mutant

  • MGNA-C415 (yqhJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2413 NBRP B. subtilis, Japan]
  • References

  • 12107147,15472076