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yerA
similar to adenine desaminase
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue][category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
713,664 → 715,406
The protein
Catalyzed reaction/ biological activity
adenine + H+ + H2O --> hypoxanthine + NH4+ (according to UniProt)Protein family
[SW|Metallo-dependent hydrolases superfamily] (according to UniProt)Modification
phosphorylation on Ser-399 [Pubmed|17218307]Expression and Regulation
Operons
genes
[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]-[gene|BE1F7BA77CE8B6A1A2D22F31421C27F2E954816A|yerB]-[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-A910 (yerA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/910 NBRP B. subtilis, Japan]BKE06560 (Δ[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE06560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCACATACTCTCCTTTA, downstream forward: _UP4_TAAAATATAAAAGAGCAGGGBKK06560 (Δ[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK06560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCACATACTCTCCTTTA, downstream forward: _UP4_TAAAATATAAAAGAGCAGGGReferences