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glnT
glutamine transporter (proton symport)
function
glutamine uptake
product
glutamine transporter (proton symport)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.1|Solute:sodium symporter family][category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.3|Alanine or glycine cation symporter family][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.1|Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.1|Utilization of glutamine/ glutamate][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
262,732 → 264,168
The protein
Protein family
[SW|Alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family] (according to UniProt)Paralogous protein(s)
[protein|B84BE9F5BEFE3A295ED5580D66040CD28609A6A1|AlsT], [protein|A69E7536DFE6353C4CD1B09D1258C88BF0FB8B4D|YflA], [protein|A10EA56A7EDA2DF712B5BB87D94A818E39940B44|YrbD] Structure
[PDB|6CSE] (from Methanococcus maripaludis), 37.4% identity [pubmed|30659158][SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|1A415DC85354373EA4866733C3AE43F510BD3C56|glsA]-[gene|E371BC4F613C40CB0E8C8CAA97387F3E6735D813|glnT]
description
[Pubmed|15995196]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|15995196], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|4E6EA2EABBDAA427E8F9EE1AE1800AF8657CF18B|GlnL]: activation, [Pubmed|15995196], in [regulon|4E6EA2EABBDAA427E8F9EE1AE1800AF8657CF18B|GlnL regulon]regulation
induced in the presence of glutamine ([protein|search|GlnL]) [Pubmed|15995196]view in new tabBiological materials
Mutant
GP3503 (Δ[gene|E371BC4F613C40CB0E8C8CAA97387F3E6735D813|glnT]::kan), available in [SW|Jörg Stülke]'s labMGNA-B942 ([gene|E371BC4F613C40CB0E8C8CAA97387F3E6735D813|glnT]::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1941 NBRP B. subtilis, Japan]BKE02420 (Δ[gene|E371BC4F613C40CB0E8C8CAA97387F3E6735D813|glnT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE02420 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGAATCACCTCTTTTTT, downstream forward: _UP4_TAAGAAAAGGGTGTTCAGACBKK02420 (Δ[gene|E371BC4F613C40CB0E8C8CAA97387F3E6735D813|glnT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK02420 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGAATCACCTCTTTTTT, downstream forward: _UP4_TAAGAAAAGGGTGTTCAGACReferences