yisP [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

farnesyl diphosphate phosphatase, production of farnesol

locus: BSU10810

pI: 7.00

mw: 31.00 kDa

function: control of KinC activity

product: farnesyl diphosphate phosphatase

essential: no

synonyms: yucD

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.3|Biosynthesis of isoprenoids]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay]
• [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation]
• [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.5|Other proteins required for biofilm formation]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of lipids], [SW|phosphorelay], [SW|biofilm formation], [SW|general stress proteins (controlled by SigB)]

This gene is a member of the following [SW|regulons]

• [SW|SigB regulon]

Gene

Coordinates on the chromosome (coding sequence): 1,159,922 -> 1,160,746

Phenotypes of a mutant

• complete loss of pellicle-forming ability [Pubmed|20713508]
• reduced [SW|protein secretion] [Pubmed|23651456]

The protein

Catalyzed reaction/ biological activity

• farnesyl diphosphate --> farnesol [Pubmed|25308276]

[SW|Cofactors]

• NADH [Pubmed|20713508]

Structure

• [PDB|3WE9] [Pubmed|25308276]

Expression and Regulation

[SW|Sigma factor]

• [SW|SigB] [Pubmed|26577401]

References

Reviews

• 25457121,25652542

Original publications

• 20713508,19935659,23651456,23295493,25308276,26577401