SubtiBank SubtiBank
ffh
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ffh

signal recognition particle (SRP) component
locus
BSU_15980
pI
9.42
mw
49.38 kDa
protein length
446 aa Sequence Blast
gene length
1341 bp Sequence Blast
function
presecretory protein translocation
product
signal recognition particle (SRP) component
essential
yes
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • Gene

    Coordinates
    1,672,174 → 1,673,514

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Protein family

  • GTP-binding SRP family (with [protein|BB6F5D7463EF96E2C6344D0BC30A227C5E3B5817|FlhF] and [protein|D519765BF5261E48512CE86245BD7B733F188D4A|FtsY], according to UniProt)
  • Structure

  • [PDB|4UE4] (complex [protein|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|Ffh]-[protein|097C817A5A3E31F73F6ABC4AA95852A64E43A057|Scr] RNA) [Pubmed|26344568]
  • [SW|Localization]

  • cytoplasm (according to UniProt)
  • Expression and Regulation

    Operons

    genes
    [gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]-[gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]-[gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP]-[gene|67FB5F6FB0B2701BD8E4FDD8DF06B236DE6A2599|ylqC]-[gene|0AB1FB44E8F28944B82B5EF14A9CDCFEE46DB76B|ylqD]-[gene|34B0FA6E7E25D1E5D8A54B70F5562BD0BD05B498|rimM]-[gene|885ECD9FAAC8BC95D32F049825D6B6244C046112|trmD]-[gene|51368512B8322EDBCA92674EC2B97CF26087D8A9|rplS]
    description
    [Pubmed|29794222]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8335643], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • regulation

  • the mRNA is processed between [gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh] and [gene|25C4850812DC216C1BEFBF07DCA71CC6820930B0|rpsP] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|YmcA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|YlbF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|YaaT] complex [Pubmed|29794222]
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    References

    Reviews

  • 25212246,27890920
  • Original publications

  • 16705751,9346318,9880811,8335643,21330537,23563142,24659773,26344568,29794222