SubtiBank SubtiBank
nasC [Mon Aug 31 2015 13:52:21 GMT+0200 (CEST)]
SAVE THE DATE! 21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.

nasC [Mon Aug 31 2015 13:52:21 GMT+0200 (CEST)]

nitrate reductase (catalytic subunit)
locus
BSU03310
pI
6.73
mw
78.00 kDa
function
utilization of nitrate
product
nitrate reductase (catalytic subunit)
essential
no
synonyms
narB, nasBB

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.1|Utilization of nitrate/ nitrite]
  • syns
    narB, nasBB

    [SW|Categories] containing this gene/protein

  • [SW|utilization of nitrogen sources other than amino acids]
  • This gene is a member of the following [SW|regulons]

  • [SW|TnrA regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • Nitrite + acceptor = nitrate + reduced acceptor (according to Swiss-Prot)
  • Protein family

  • prokaryotic molybdopterin-containing oxidoreductase family (according to Swiss-Prot)
  • [SW|Cofactors]

  • MoCo [Pubmed|11289299]
  • Fe-S cluster [Pubmed|11289299]
  • [SW|Interactions]

  • [protein|search|NasB]-[protein|search|NasC] [Pubmed|11289299]
  • Expression and Regulation

    Operon

  • ''[protein|search|nasB]-[protein|search|nasC]-[protein|search|nasD]-[protein|search|nasE]-[protein|search|nasF]'' [Pubmed|7836289]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|7836289]
  • Regulation

  • expressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|8799114]
  • induced by nitric oxide under anaerobic conditions ([protein|search|NsrR]) [Pubmed|16885456]
  • Regulatory mechanism

  • [protein|search|TnrA]: transcription activation [Pubmed|8799114]
  • [protein|search|NsrR]: transcription repression [Pubmed|16885456]
  • References

    Reviews

  • 22103536,11289299
  • Original publications

  • 12823818,7868621,25755103,8799114,16885456