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rplK
product
ribosomal protein L11 (BL11)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.9|Newly identified competence genes][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue][category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins]Gene
Coordinates
118,591 → 119,016
Phenotypes of a mutant
poor growth [pubmed|28189581]non-transformable [pubmed|28189581]The protein
Protein family
Universal [SW|ribosomal protein] uL11 family (single member, according to UniProt)Modification
phosphorylated on Arg-94 [Pubmed|22517742]Structure
[PDB|1FOX] (C-terminal domain, Geobacillus stearothermophilus)[PDB|2FOW] (RNA binding domain in complex with RNA, Geobacillus stearothermophilus)[PDB|3J9W] (the [SW|ribosome]) [Pubmed|25903689][SW|Localization]
[SW|ribosome] (according to UniProt)Expression and Regulation
Operons
genes
[gene|F94A1C14912F35ADB4C611AA17D55268CC26160D|rplK]-[gene|44D4CE353E1E532664A508CBE8B49AC8BB861B53|rplA]-[gene|E4D89640D0F0A31A2814D20FB5425FDB0B46A43D|BSU_misc_RNA_3]-[gene|5EF3A7953AA97D2B44C967542A53FEA7F36D7BA3|rplJ]-[gene|E72910604D3DC2A62AE8A951F55570EA2838B250|rplL]
description
[pubmed|22383849]
regulatory mechanism
[regulon|stringent response|stringent response]: negative regulation, [pubmed|11948165], in [regulon|stringent response|stringent response]regulation
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]view in new tabBiological materials
Mutant
BKE01020 (Δ[gene|F94A1C14912F35ADB4C611AA17D55268CC26160D|rplK]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE01020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGAGACACACCTCCTTAA, downstream forward: _UP4_TAATTTGTTTCTTGTCGGGTBKK01020 (Δ[gene|F94A1C14912F35ADB4C611AA17D55268CC26160D|rplK]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK01020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGAGACACACCTCCTTAA, downstream forward: _UP4_TAATTTGTTTCTTGTCGGGTReferences
11244072,11948165,19653700,20441189,20525796,22517742,112097,23002217,25903689,28516784,28189581