nadF

nadF
168

NAD kinase

locus
BSU_11610
Molecular weight
29.86 kDa
pI
5.99
Protein length
Gene length
function
generation of NADP from NAD
product
inorganic polyphosphate/ATP-NAD kinase
essential
yes
ec
2.7.1.23
synonyms
nadF, yjbN, ppnK, ppnKA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0061

This gene is a member of the following regulons

Gene
Coordinates
1,237,660  1,238,460
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
ATP + NAD+ --> ADP + H+ + NADP+ (according to UniProt)
Protein family
NAD kinase family (with [protein|B729EFC0BF0D75765C2D2B0B4F397E0AEE11F1E7|ytdI], according to UniProt)
Structure
[PDB|2I1W] (from ''Listeria monocytogenes'', 60% identity) [Pubmed|17686780]
[AF|O31612]
Effectors of protein activity
allosterically activated by quinolinic acid
Paralogous protein(s)
[protein|B729EFC0BF0D75765C2D2B0B4F397E0AEE11F1E7|ytdI]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|E5A57660B69F9E9BC52FD9C8A5E3C8786CE96728|yjbL]-[gene|81BCF5C08EC1A580F5E05884BA830130FC7E46E9|sasB]-[gene|2A2640A0501ECEA44A3C0C4842FAC053FB422A1F|nadF]-[gene|2AECDA9C4D0E704976B9E2168722EC80FE7A256D|yjbO]
description
[Pubmed|18067544]
regulation
expressed during exponential growth
Open in new tab

[gene|E5A57660B69F9E9BC52FD9C8A5E3C8786CE96728|yjbL]→[gene|2AECDA9C4D0E704976B9E2168722EC80FE7A256D|yjbO]

2022-11-30 18:37:17

Jstuelk

32

c5edd61e714281007d4d9ec99a1efa0cfef63f09

83E46551CBC32AB07130281546FE3D422612C2C3

Biological materials
Mutant
MGNA-B160 (yjbN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1159 NBRP B. subtilis, Japan]
1A825 ( ''nadF''::''erm''), [Pubmed|12682299], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A825&Search=1A825 BGSC]
References
12897004,18067544,17686780

2A2640A0501ECEA44A3C0C4842FAC053FB422A1F

Page visits: 1902

Time of last update: 2022-12-04 21:00:07

Author of last update: Melvin.boenninger