gatC

At Gram+ 2022 in Prague, there will be a workshop on how to get the most out of SubtiWiki. We will present newly added features. Moreover, we hope to learn from you what you would like to have added to SubtiWiki to improve it!

gatC
168

production of glutamyl-tRNA(Gln)

locus
BSU_06670
Molecular weight
10.72 kDa
pI
4.6
Protein length
Gene length
function
translation
product
glutamyl-tRNA(Gln) amidotransferase (subunit C)
essential
yes
ec
6.3.5.7
synonyms
gatC, yerL, yedA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0721

This gene is a member of the following regulons

Gene
Coordinates
728,732  729,022
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
ATP + H2O + L-glutamine + L-glutamyl-tRNAGln --> ADP + H+ + L-glutamate + L-glutaminyl-tRNAGln + phosphate (according to UniProt)
ATP + H2O + L-aspartyl-tRNAAsn + L-glutamine --> ADP + 2 H+ + L-asparaginyl-tRNAAsn + L-glutamate + phosphate (according to UniProt)
Protein family
gatC family (single member, according to UniProt)
Structure
[PDB|2DF4] ([protein|FA88576A405F8C92C83BE74985039DC02E1F6C94|gatA]-[protein|F9C088D2DB3E99FDF961DE1B78A9B81279F204C9|gatB]-[protein|4A6AB40A91B4821B99E2FECD1C4E523321B8BDEA|gatC] complex from ''Staphylococcus aureus'') [Pubmed|16809541]
[AF|O06492]
Modification
phosphorylated on Arg-3 [Pubmed|22517742]
Expression and Regulation
Operons
genes
[gene|4A6AB40A91B4821B99E2FECD1C4E523321B8BDEA|gatC]-[gene|FA88576A405F8C92C83BE74985039DC02E1F6C94|gatA]-[gene|F9C088D2DB3E99FDF961DE1B78A9B81279F204C9|gatB]
description
[pubmed|22383849]
Open in new tab

[gene|4A6AB40A91B4821B99E2FECD1C4E523321B8BDEA|gatC]→[gene|F9C088D2DB3E99FDF961DE1B78A9B81279F204C9|gatB]

2022-04-27 14:05:08

Jstuelk

25

005a04d4930d179ec4f73ac831d690493cc6a205

45B867D63B0D40557C698DD1870A35EA13FC36C6

Biological materials
Mutant
MGNA-A928 (yerL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/928 NBRP B. subtilis, Japan]
References
9342321,20882017,22517742,16809541

4A6AB40A91B4821B99E2FECD1C4E523321B8BDEA

Page visits: 2421

Time of last update: 2022-05-19 08:07:31

Author of last update: Melvin.boenninger