csoR

csoR
168

transcription repressor of [gene|18506FB74F6BB9278F22EB7DCDA3CF72575CC32A|copZ]-[gene|727024F7B1AC19676ED4B516CF46A47B1328310B|copA]

locus
BSU_33520
Molecular weight
11.34 kDa
pI
7.3
Protein length
101 aaSequenceBlast
Gene length
306 bpSequenceBlast
function
control of copper homeostasis
product
transcription repressor
essential
no
synonyms
csoR, yvgZ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1937 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,443,896  3,444,201
The protein
Protein family
CsoR family (single member, according to UniProt)
Structure
[PDB|4M1P] (from Geobacillus thermodenitrificans, 59% identity) [pubmed|24831014]
[AF|O32222]
Effectors of protein activity
Cu(I) ions cause release of CsoR from its operator sites
Expression and Regulation
Operons
genes
[gene|6977F18870004AD236539D9409255815E6BE9241|csoR]-[gene|18506FB74F6BB9278F22EB7DCDA3CF72575CC32A|copZ]-[gene|727024F7B1AC19676ED4B516CF46A47B1328310B|copA]
description
[Pubmed|22383849]
Open in new tab

[gene|6977F18870004AD236539D9409255815E6BE9241|csoR]→[gene|727024F7B1AC19676ED4B516CF46A47B1328310B|copA]

2025-07-10 07:13:42

Jstuelk

110

eb86b49e4fa20367c75145f1a228f37db4b5da04

AAFF284B2BD1673523D4C48EA1D3231D7A156AFC

Biological materials
Mutant
MGNA-B604 (yvgZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1603 NBRP B. subtilis, Japan]
BKE33520 ([gene|6977F18870004AD236539D9409255815E6BE9241|csoR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33520 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGCGTACACCTCTGTTTA,  downstream forward: _UP4_TAAAGCGTTTTTTATTGTAA
BKK33520 ([gene|6977F18870004AD236539D9409255815E6BE9241|csoR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33520 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGCGTACACCTCTGTTTA,  downstream forward: _UP4_TAAAGCGTTTTTTATTGTAA
labs
[wiki|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
[wiki|Mohamed Marahiel], Marburg University, Germany [http://www.uni-marburg.de/fb15/fachgebiete/bio/marahiel?language_sync=1 homepage]
References
Reviews
22918892,25209494,39658019
Original Publications
18048925,19168619,20233928,19168619,19249860,24831014

6977F18870004AD236539D9409255815E6BE9241

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Time of last update: 2025-07-16 10:40:44

Author of last update: Jstuelk