dnaX

dnaX
168

DNA polymerase III (gamma and tau subunits) part of the clamp-loader complex and the [wiki|replisome]

locus
BSU_00190
Molecular weight
62.53 kDa
pI
5.49
Protein length
Gene length
function
[category|SW.3.1.1|DNA replication]
product
DNA polymerase  III (gamma and tau subunits)
essential
yes
ec
2.7.7.7
synonyms
dnaX, dnaH, dna-8132

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2812

This gene is a member of the following regulons

Gene
Coordinates
26,814  28,505
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
deoxyribonucleoside 5'-triphosphate + DNA(n) --> diphosphate + DNA(n+1) (according to UniProt)
required for bacteriophage SPP1 replication [Pubmed|23268446]
Protein family
DnaX/STICHEL family (single member, according to UniProt)
Structure
[PDB|1JR3] (from ''E. coli'', 39% identity) [Pubmed|11525729]
[AF|P09122]
[wiki|Localization]
forms foci [Pubmed|21958350]
Nucleoid (Mid-cell) [Pubmed|16479537]
Expression and Regulation
Operons
genes
[gene|73D063EDC412F7F28DA27C986ECCCD1C4A1F6618|dnaX]-[gene|9AFCEFE83560B1E2B1FFD7CFD2E4F17FAE137889|yaaK]-[gene|BEBAF1EB53EBB3E7558BB5FE73C418B50000FA29|recR]-[gene|C5127208E7562F09249112240F0BE8C582B2E5AD|yaaL]-[gene|CB5D3A2E5BEE336539BEB2D7C5D9C3A63C78FD01|bofA]
description
[Pubmed|22383849]
Open in new tab

[gene|73D063EDC412F7F28DA27C986ECCCD1C4A1F6618|dnaX]→[gene|CB5D3A2E5BEE336539BEB2D7C5D9C3A63C78FD01|bofA]

2022-12-01 05:47:42

Jstuelk

53

1a32cdecddaee24171f48459041fdcb062bafc36

7EC4B7D4D9D0E5E8848420FD5562059E4207233C

References
16479537,19415803,14757052,12974630,1703271,12466528,20122408,23525462,23268446,21958350,11525729,30686488

73D063EDC412F7F28DA27C986ECCCD1C4A1F6618

Page visits: 5624

Time of last update: 2022-12-01 09:48:14

Author of last update: TPed