serS
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serS
168

seryl-tRNA-synthetase

locus
BSU_00130
Molecular weight
48.68 kDa
pI
5.19
Protein length
Gene length
function
translation
product
seryl-tRNA-synthetase
essential
yes
ec
6.1.1.11
synonyms
serS

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0172

This gene is a member of the following regulons

Gene
Coordinates
20,880  22,157
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
ATP + L-serine + tRNA(Ser) --> AMP + diphosphate + L-seryl-tRNA(Ser) (according to UniProt)
Protein family
[wiki|Class-II aminoacyl-tRNA synthetase family] (according to UniProt)
Structure
[PDB|1SES] (from ''Thermus thermophilus'', 36% identity, 56% similarity) [Pubmed|8128224]
[AF|P37464]
[wiki|Localization]
cytoplasm (according to UniProt)
Expression and Regulation
Operons
genes
[gene|82B92D2FB8DB88689D3A8B77FAD2F63FCCA04C7E|serS]
description
[Pubmed|8915527]
regulation
induced by serine limitation ([protein|search|T-box]) [Pubmed|19258532]
regulatory mechanism
T-box: anti-termination, in [regulon|other_regulator:T-box|T-box]
Open in new tab

[gene|82B92D2FB8DB88689D3A8B77FAD2F63FCCA04C7E|serS]

2022-07-21 11:37:24

ghost

27

1c8cadaecb8ad0dd5fad01ee119f508324846630

13BA919556DD76D4D09C5E095C58D3265843EAF8

genes
[gene|7C3081BC8D416127A881627EB56C0628359111CF|dacA]-[gene|651D1E534490276B9BE7BFE7B5819176AE09891E|pdxS]-[gene|6F96C10759C1C20B3A6B396E3718F0A9281F100A|pdxT]-[gene|82B92D2FB8DB88689D3A8B77FAD2F63FCCA04C7E|serS]
description
[Pubmed|22383849]
regulation
the leader mRNA is processed upstream of [gene|7C3081BC8D416127A881627EB56C0628359111CF|dacA] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|ymcA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|ylbF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|yaaT] complex [Pubmed|29794222]
Open in new tab

[gene|7C3081BC8D416127A881627EB56C0628359111CF|dacA]→[gene|82B92D2FB8DB88689D3A8B77FAD2F63FCCA04C7E|serS]

2022-07-21 10:23:00

Jstuelk

41

4760e1ef503f91543fe562a8e6f81fd9fdcc9c0c

59F563C38B7236ABF3A723D4A694F254F7E01503

genes
[gene|651D1E534490276B9BE7BFE7B5819176AE09891E|pdxS]-[gene|6F96C10759C1C20B3A6B396E3718F0A9281F100A|pdxT]-[gene|82B92D2FB8DB88689D3A8B77FAD2F63FCCA04C7E|serS]
description
[Pubmed|22383849]
Open in new tab

[gene|651D1E534490276B9BE7BFE7B5819176AE09891E|pdxS]→[gene|82B92D2FB8DB88689D3A8B77FAD2F63FCCA04C7E|serS]

2022-07-21 10:20:18

Jstuelk

39

3a39773e030831d4f4c2ea2177325068c250716a

FEDBE769AE13F9FC0C403044E49C379680B12566

References
19258532,8915527

82B92D2FB8DB88689D3A8B77FAD2F63FCCA04C7E

Page visits: 1888

Time of last update: 2022-08-09 05:29:55

Author of last update: Melvin.boenninger