chaA
168
H+/Ca2+ exchanger
locus
BSU_07920
Molecular weight
37.37 kDa
pI
5.21
function
calcium export
product
calcium export via proton antiporter
essential
no
synonyms
chaA, yfkE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0387 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
865,205 866,260
The protein
Protein family
Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family (single member, according to UniProt)
Structure
[PDB|4KJS] [Pubmed|23798403]
[AF|O34840]
[wiki|Localization]
cell membrane [Pubmed|30602489,23798403]
Expression and Regulation
Operons
genes
[gene|977695DBD3FF4C823E1A46E06C46706254F80891|chaA]-[gene|95B85312D4647B94AF04B912F818AB8345CCDCFD|yfkD]
description
[Pubmed|19543710]
regulation
expressed in the forespore ([protein|search|SigG]) [Pubmed|19543710]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|19543710], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
Biological materials
Mutant
MGNA-C269 (yfkE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2267 NBRP B. subtilis, Japan]
BKE07920 ([gene|977695DBD3FF4C823E1A46E06C46706254F80891|chaA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE07920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTGAAATAGCTCCTTT, downstream forward: _UP4_TAACCTGAAAAAATGATGGA
BKK07920 ([gene|977695DBD3FF4C823E1A46E06C46706254F80891|chaA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK07920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTGAAATAGCTCCTTT, downstream forward: _UP4_TAACCTGAAAAAATGATGGA
References
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Time of last update: 2025-07-24 14:04:15
Author of last update: Jstuelk