nox
168
NADH oxidase
locus
BSU_19550
Molecular weight
22.19 kDa
pI
5.27
function
regeneration of NAD from NADH
product
NADH oxidase
essential
no
synonyms
yodC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0778 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,127,813 → 2,128,421
The protein
Catalyzed reaction/ biological activity
NADH + H+ + O2 --> NAD+ + H2O [Pubmed|37106723,26312069]
Protein family
[wiki|nitroreductase family] (according to UniProt)
[wiki|Cofactors]
FAD [Pubmed|37106723]
Structure
[PDB|3GE6] (from '' Exiguobacterium sibiricum'', 42% identity)
[AF|P81102]
Expression and Regulation
Operons
genes
[gene|BC434FE0E92376A618ED34ACBB07B8A2E7F31DE6|nox]
description
[pubmed|22383849]
regulatory mechanism
[protein|73AFDF65BE89C0E2CC59AF2AF64C29BD99D785DF|yodB]: repression, [Pubmed|18208493], in [regulon|protein:73AFDF65BE89C0E2CC59AF2AF64C29BD99D785DF|yodB regulon]
Biological materials
Mutant
MGNA-B434 (yodC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1433 NBRP B. subtilis, Japan]
BKE19550 (Δ[gene|BC434FE0E92376A618ED34ACBB07B8A2E7F31DE6|nox]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE19550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGTGTTTCCTCCTTCGG, downstream forward: _UP4_TAAGGATATGAAAAACCTTA
BKK19550 (Δ[gene|BC434FE0E92376A618ED34ACBB07B8A2E7F31DE6|nox]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK19550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGTGTTTCCTCCTTCGG, downstream forward: _UP4_TAAGGATATGAAAAACCTTA
References
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Time of last update: 2025-07-16 18:25:08
Author of last update: Jstuelk