spoVAF

spoVAF
168

essential for the uptake of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2 ) into developing spores, required for spore maturation

locus
BSU_23390
Molecular weight
55.44 kDa
pI
6.21
Protein length
493 aaSequenceBlast
Gene length
1482 bpSequenceBlast
function
spore maturation
product
unknown
essential
no
synonyms
spoVAF
Outlinks
BsubCyc SubtiList UniProt STRING Expression Browser PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5840

This gene is a member of the following regulons

Gene
Coordinates
2,438,372 → 2,439,853
Phenotypes of a mutant
delayed germination with germinant receptor-dependent germinants [Pubmed|24682327]
The protein
Protein family
[wiki|GerABKA family] (according to UniProt)
Structure
[AF|P31845]
[wiki|Localization]
integral inner spore membrane protein [Pubmed|24682327]
Expression and Regulation
Operons
genes
[gene|5410018998EC9792A69CF0D9C438EEF5AC8A82C5|spoVAA]-[gene|AEC70413BDC29F435776D532E7049AA9A0BD893D|spoVAB]-[gene|B280951A232E941FB0A6C8834049765BE1E16437|spoVAC]-[gene|9531F0A0DC4AE5696FFBAC9C2A773F15840E3255|spoVAD]-[gene|31D6CB7EC20C39C1815CA4552B8B9C4BE304E86B|spoVAEB]-[gene|B44529B69769D7AF1010E06C95E398EA91A3E798|spoVAEA]-[gene|CBE5093DFBBCE25071CCE12408BC9AFF7A158C03|spoVAF]-[gene|02F1C926D200DE85C93A0ACEF23AD25FBD12B0BD|lysA]
description
[Pubmed|7934830]
regulation
expressed late during sporulation in the forespore ([protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG], [wiki|SpoVT]) [Pubmed|15699190,1903432,8755877]
regulatory mechanism
[protein|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]: activation, [Pubmed|8755877], in [regulon|protein:01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT regulon]
sigma factors
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|15699190,1903432], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
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[gene|5410018998EC9792A69CF0D9C438EEF5AC8A82C5|spoVAA]→[gene|02F1C926D200DE85C93A0ACEF23AD25FBD12B0BD|lysA]

2023-02-02 01:13:33

Jstuelk

32

12fce0add6fb0abbed0128cd99d7be2c377e96d5

420F73950DA10EFCB3126E84B350E66BA95D34DD

Biological materials
Mutant
BKE23390 (Δ[gene|CBE5093DFBBCE25071CCE12408BC9AFF7A158C03|spoVAF]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23390 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_ACGGTTTTTGAAATACTCTT,  downstream forward: _UP4_TAATCGCATTGAAACTGACT
BKK23390 (Δ[gene|CBE5093DFBBCE25071CCE12408BC9AFF7A158C03|spoVAF]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23390 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_ACGGTTTTTGAAATACTCTT,  downstream forward: _UP4_TAATCGCATTGAAACTGACT
References
Reviews
35638784
Original Publications
3114420,11751839,15451103,3926949,17158659,6432957,7934830,22328679,15699190,1903432,8755877,21398556,24682327,26731423

CBE5093DFBBCE25071CCE12408BC9AFF7A158C03

Page visits: 1443

Time of last update: 2023-02-03 06:44:22

Author of last update: Jstuelk