ppsD

ppsD
168

plipastatin synthetase

locus
BSU_18310
Molecular weight
406.42 kDa
pI
5.35
Protein length
Gene length
function
production of the antibacterial compound plipastatin
product
plipastatin synthetase
essential
no
synonyms
ppsD

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4908

This gene is a member of the following regulons

Gene
Coordinates
1,964,045 → 1,974,856
Phenotypes of a mutant
defective in sporulation timing [pubmed|34460312]
The protein
Protein family
[wiki|ATP-dependent AMP-binding enzyme family] (according to UniProt)
[wiki|Domains]
3 [wiki|Carrier domain]s (aa 966-1041, aa 1997-2072, aa 3034-3108) (according to UniProt)
Structure
[PDB|2VSQ] (termination module of [protein|1D5F227860A321506A1AB4BAE63CAD3A66E43BFC|srfAC], 38% identity) [pubmed|18583577]
Expression and Regulation
Operons
genes
[gene|E3D7EF8F165CAC2682B0D620081C5C6E555E43C4|ppsA]-[gene|E7A2F93B33B1899313893D362D92405232BC9097|ppsB]-[gene|D11CE89E2AC2ADE3FEFEC261E295EC5906CE6407|ppsC]-[gene|E73D9F1A8F54DAD4B2056CABBE580D7AD36CB042|ppsD]-[gene|C1C051209943E02369356075EAA733297E9478CB|ppsE]
description
[Pubmed|20817675]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
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[gene|E3D7EF8F165CAC2682B0D620081C5C6E555E43C4|ppsA]→[gene|C1C051209943E02369356075EAA733297E9478CB|ppsE]

2022-11-24 21:58:46

ghost

22

c24e95905169206a2bb4f32c2e44eb72392e19bb

53EB981BAF3A634ABF820E4DAD645D458FD52A47

Biological materials
Mutant
BKE18310 (Δ[gene|E73D9F1A8F54DAD4B2056CABBE580D7AD36CB042|ppsD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE18310 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTTCATGTCTCCTGTCA,  downstream forward: _UP4_ATGCTCAGTTTTCACTAATG
BKK18310 (Δ[gene|E73D9F1A8F54DAD4B2056CABBE580D7AD36CB042|ppsD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK18310 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTTCATGTCTCCTGTCA,  downstream forward: _UP4_ATGCTCAGTTTTCACTAATG
References
10471562,9387222,22347779,20817675,18583577,29855381,34460312

E73D9F1A8F54DAD4B2056CABBE580D7AD36CB042

Page visits: 2838

Time of last update: 2022-11-27 04:21:45

Author of last update: Jstuelk