divIC

divIC
168

cell-division initiation protein (septum formation), component of septosome (with [protein|B66FC02948DABBCE64DE2629D6E33E05647B4EEF|divIB])

locus
BSU_00620
Molecular weight
14.58 kDa
pI
9.97
Protein length
Gene length
function
septum formation
product
cell-division protein, member of the [wiki|divisome]
essential
yes
synonyms
divIC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2919

This gene is a member of the following regulons

Gene
Coordinates
69,168 → 69,545
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
stabilizes [protein|79712F4CF884A660C71B45B3397AEFA5C0AFA683|ftsL] against [protein|CB50289535EA537F63BADD459BD11AA7759A6658|rasP] cleavage [Pubmed|20644139]
Structure
[AF|P37471]
[wiki|Localization]
membrane bound [Pubmed|9426141]
Expression and Regulation
Operons
genes
[gene|D6B1837075ECBEE1FEAC704DDB6795336092897F|yabM]-[gene|52D48F22CB53421EE30970D34B4861E2F8A5893D|yabN]-[gene|B0CB19A3E3E84E12BF42BB050394C8A059A89359|rqcP]-[gene|035B5486A3887FC71ACC0A8FB43ED77DC44E12EA|yabP]-[gene|4DEDB27C0162409571AB4A1BB17CFE400764AE45|yabQ]-[gene|FE0E60B875E72AEF5174A89C7AE5556FF59B19D5|divIC]-[gene|8EDB1BCEEE64FDAF1C9054300751FCB420658865|yabR]
description
[Pubmed|11283287]
regulation
expressed during sporulation ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]) [Pubmed|11283287]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]: sigma factor, [Pubmed|18179421], in [regulon|protein:081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190,11283287], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
[protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]: sigma factor, [Pubmed|12207695], in [regulon|protein:3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW regulon]
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|26577401], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
[protein|E77364F274A520FCCA9F5C9504E317B047BA29E6|sigX]: sigma factor, [Pubmed|12207695], in [regulon|protein:E77364F274A520FCCA9F5C9504E317B047BA29E6|sigX regulon]
Open in new tab

[gene|D6B1837075ECBEE1FEAC704DDB6795336092897F|yabM]→[gene|8EDB1BCEEE64FDAF1C9054300751FCB420658865|yabR]

2022-06-08 00:34:32

Jstuelk

36

93952be38722510f984794e138450cd80a9f7d48

0CF3909333400A3BFE18E32016883124FFC3D75B

genes
[gene|035B5486A3887FC71ACC0A8FB43ED77DC44E12EA|yabP]-[gene|4DEDB27C0162409571AB4A1BB17CFE400764AE45|yabQ]-[gene|FE0E60B875E72AEF5174A89C7AE5556FF59B19D5|divIC]-[gene|8EDB1BCEEE64FDAF1C9054300751FCB420658865|yabR]
description
[Pubmed|11283287]
regulation
expressed during sporulation ([protein|search|SigE]) [Pubmed|11283287]
additional information
there are about 50,000 molecules of DivIC per cell [http://www.ncbi.nlm.nih.gov/sites/entrez/9426141 PubMed]
Open in new tab

[gene|035B5486A3887FC71ACC0A8FB43ED77DC44E12EA|yabP]→[gene|8EDB1BCEEE64FDAF1C9054300751FCB420658865|yabR]

2022-06-08 09:34:26

ghost

20

adf8aab8f33a2b64c2ab3f1426fc15c0793898c5

4D8628337CAF16F8F83A7EEB7090199FCE86D5A2

genes
[gene|FE0E60B875E72AEF5174A89C7AE5556FF59B19D5|divIC]-[gene|8EDB1BCEEE64FDAF1C9054300751FCB420658865|yabR]
description
[Pubmed|11283287]
regulation
expressed during sporulation ([protein|search|SigE]) [Pubmed|11283287] and under stress conditions
additional information
there are about 50,000 molecules of DivIC per cell [http://www.ncbi.nlm.nih.gov/sites/entrez/9426141 PubMed]
Open in new tab

[gene|FE0E60B875E72AEF5174A89C7AE5556FF59B19D5|divIC]→[gene|8EDB1BCEEE64FDAF1C9054300751FCB420658865|yabR]

2022-06-12 11:18:30

ghost

22

e89ee3da1e193a6ce32d5415440bb9ce9c84e21b

8A082EECE8DFD692079BAE5CA83770CB2A839351

additional information
there are about 50,000 molecules of DivIC per cell [pubmed|9426141]
Biological materials
FLAG-tag construct
GP2006 ''divIC-3xFLAG ermC'' (based on [wiki|pGP1087]), available in [wiki|Jörg Stülke]'s lab
References
Reviews
35638784
Original Publications
18179421,16936019,10217758,9720875,8113187,10323866,9426141,10852898,10844672,11283287,11994149,20870765,25176632,20644139,29443967,33077634,33737746

FE0E60B875E72AEF5174A89C7AE5556FF59B19D5

Page visits: 4786

Time of last update: 2022-06-24 20:29:38

Author of last update: Jstuelk