brxA

brxA
168

bacilliredoxin

locus
BSU_21860
Molecular weight
15.73 kDa
pI
4.62
Protein length
Gene length
function
de-bacillithiolation of S-bacillithiolated [protein|7A3A8AF7728474204396BB7A548F747D28E6FAC7|ohrR] and [protein|23F405D5B849E4EDC1D599F86C71DFD2E55C0305|metE]
product
bacilliredoxin
essential
no
synonyms
brxA, yphP

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
2,300,221 → 2,300,655
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The protein
Catalyzed reaction/ biological activity
de-bacillithiolation of S-bacillithiolated [protein|7A3A8AF7728474204396BB7A548F747D28E6FAC7|ohrR] and [protein|23F405D5B849E4EDC1D599F86C71DFD2E55C0305|metE] [Pubmed|24313874]
Protein family
UPF0403 family (with [protein|8B134BDC82C92DB7747A3AF291C96BB0F223D0CF|brxB], according to UniProt)
[wiki|Domains]
contains an CxC redox motif [Pubmed|20308541]
Structure
[PDB|3FHK] [Pubmed|19653655]
[AF|P54170]
Modification
S-bacillithiolation upon hypochlorite stress on Cys-53 [Pubmed|21749987]
Paralogous protein(s)
[protein|8B134BDC82C92DB7747A3AF291C96BB0F223D0CF|brxB]
Expression and Regulation
Operons
genes
[gene|FBE3C55526FE0CBBDA71AE0B0D7C6AD074E8A63E|brxA]
description
[Pubmed|22383849]
Open in new tab

[gene|FBE3C55526FE0CBBDA71AE0B0D7C6AD074E8A63E|brxA]

2024-03-27 09:00:46

Jstuelk

52

05c2e1b3b9538bc38b455a8f2a2d0f461d81441e

430FD8467CF16D52D5D76BD4A4FBA15D9E7B0A50

genes
[gene|FBE3C55526FE0CBBDA71AE0B0D7C6AD074E8A63E|brxA]-[gene|4E06C3D56DC798E19DD166CEE4921EB8F1DC0168|ypiP]
description
[Pubmed|22383849]
Open in new tab

[gene|FBE3C55526FE0CBBDA71AE0B0D7C6AD074E8A63E|brxA]→[gene|4E06C3D56DC798E19DD166CEE4921EB8F1DC0168|ypiP]

2024-03-01 19:10:37

Jstuelk

70

b2dae456ff8424bacd4879ea7caad26832e10db4

9AAD05AFD4D05D5812FEFBC108EFAC0498FE3DD5

Biological materials
Mutant
MGNA-A879 (yphP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/879 NBRP B. subtilis, Japan]
CS213 (''[gene|FBE3C55526FE0CBBDA71AE0B0D7C6AD074E8A63E|brxA]''::''aphA3'', available in [wiki|Colin Harwood]'s and [wiki|Jörg Stülke]'s labs) [Pubmed|27197833]
BKE21860 (Δ[gene|FBE3C55526FE0CBBDA71AE0B0D7C6AD074E8A63E|brxA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE21860 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAAAAAAAGCCCCCTCTA,  downstream forward: _UP4_TAAATGCCCGTTCTCCGGGC
BKK21860 (Δ[gene|FBE3C55526FE0CBBDA71AE0B0D7C6AD074E8A63E|brxA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK21860 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAAAAAAAGCCCCCTCTA,  downstream forward: _UP4_TAAATGCCCGTTCTCCGGGC
References
22938038,19653655,20308541,21749987,24313874,36191235

FBE3C55526FE0CBBDA71AE0B0D7C6AD074E8A63E

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Time of last update: 2024-03-29 02:03:48

Author of last update: Jstuelk